Results
, Site Lin, Mbarek, Willemsen, Dolan, Fedko and you will Abdellaoui 2015) plus the comes from the fresh new GWAS getting attention color are demonstrated on Second situation. We replicated brand new understood hereditary variants getting eye color like the HERC2 region having brownish vision colour (ideal SNP: rs74940492, Otherwise = 0.09, p = 5.4E-8) and for blue/grey eye colour (top SNP: rs2240202, Otherwise = , p = 1.0E-47); TYR and you may SLC24A4 for blue/grey (best SNPs: rs4904871, Otherwise = 0.71, p = dos.8E-13; rs67279079, Otherwise = 0.70, p = 3.1E-11) and you will green/hazel eye colour (best SNPs: rs4904871, Or = step one.52, p = step three.8E-20; rs67279079, Otherwise = step 1.forty two, p = step 3.6E-10). Of the recognized pigment genetic variants, we understood one HERC2 enjoys pleiotropic effects into the blonde, brownish, black tresses color and you may bluish/gray, brown eye color, and you will SLC24A4 features pleiotropic consequences into the blonde, brownish, ebony locks color and you may bluish/gray and you may green/hazel eyes colour.